Antibiotics won’t work this time? Let’s look at the attack and defense of pathogens and human body

At present, it is popular in novel coronavirus. At the same time, we also hear the news that there is no specific drug at present. Some people may ask: Why can’t we treat it with antibiotics?

Because the pathogen this time is a virus, not a bacterium!

What are the similarities and differences between viruses and bacteria? Why can’t we kill the virus with antibiotics?

Image source: veer gallery

Image source: veer gallery

Are tiny creatures on the earth.

Bacteria and viruses are microorganisms. As the smallest life form on the earth, people always ignore their existence, but this tiny creature is always painted with a sense of existence, and people will be infected by them if they are not careful.

Bacteria are cells, which have cell walls, DNA and organelles. They can produce and metabolize needed enzymes by themselves, and can divide and reproduce by themselves. Viruses are much smaller than bacteria, and the main structure is protein capsid and internal genetic material (DNA or RNA), and viruses cannot replicate themselves. Viruses need to replicate their genetic material by infecting host cells, and then release more offspring viruses to infect other host cells.

Bacteria can be harmless or even beneficial to human health, and can live independently. The purpose of the virus is to replicate itself, so it has no meaning unless it infects the host. It can be described as the purest "selfish gene".

The size difference between them is about 1000 times.

Bacteria in a broad sense are prokaryotes. Although they have a cell structure, they are still very different from human cells. Their structures are simpler, and they have no nucleus, but only a DNA aggregation area-pseudonucleus. Bacteria are generally spherical, rod-shaped, spiral, etc., and people do not forget to add a description of their shapes when naming them, such as Escherichia coli, Lactobacillus, Staphylococcus aureus and so on (ps. Yeast is a fungus, so there is no shape in the name.

At present, the smallest known bacteria are only 0.2 microns long, so they can only be seen under a microscope; The largest bacteria in the world can be directly seen by naked eyes, and it is 0.2-0.6 mm in size. It is a kind of bacteria called Sulphidophilus Namibia.

Bacterial size

Bacterial size

Virus is a noncellular form composed of a nucleic acid molecule (DNA or RNA) and protein. It lives by parasitism and is an organic species between living things and nonliving things. After it enters the cell, its metabolism such as DNA replication is indeed the characteristic of living things, while after it leaves the cell, it is just a lifeless crystal.

Novel coronavirus electron micrograph

Novel coronavirus electron micrograph  

Most viruses are between 10 and 300 nanometers (nm) in diameter. Some filamentous viruses can be as long as 1400nm, but their width is only about 80nm. Most viruses cannot be observed under optical microscope, and scanning or transmission electron microscope is the main tool to observe the morphology of virus particles. Compared with bacteria, viruses differ in size by about 1000 times.

There are also different ways to invade the human body.

There are many "good people" in bacteria, among which saprophytic bacteria are important decomposers in the ecosystem, which makes the carbon cycle go smoothly; Some bacteria will carry out nitrogen fixation, so that nitrogen can be converted into forms that can be used by biology. The production of cheese, yogurt and fermented grains, the manufacture of some antibiotics and the treatment of wastewater are all related to bacteria. In the field of biotechnology, bacteria are also widely used. Of course, the "bad guys" in bacteria are many pathogenic bacteria, including tuberculosis, anthrax, plague and other diseases are caused by bacteria.

The relationship between bacteria and human body is mainly parasitic. Let’s mainly talk about pathogenic bacteria. Because most bacteria have their own metabolic system, bacteria can be parasitic between normal cells of human body after invading human body. Bacteria take away the nutrients necessary for the body; The growth of bacteria produces various metabolites, which disrupts the physiological balance of the body; Even the size of bacteria has become a pathogenic factor, which interferes with and destroys the function of cells. Therefore, in some diseases, the proliferation of bacteria alone has fatal consequences.

Parasitic diagram of staphylococcus aureus

Parasitic diagram of staphylococcus aureus

The virus may have invaded the human body from a sneeze or a physical contact. Viruses need to parasitize in living host cells, and rely on host cells to provide the raw material system, energy and place needed for virus replication. When a virus is ready to infect a host cell, it needs the following six steps to complete its proliferation activities, namely adsorption, invasion, hulling, biosynthesis, assembly and release.

Adsorption: The virus "targets" the target cell by recognizing the specific receptor protein molecules on the surface of the host cell membrane (for example, novel coronavirus virus recognizes angiotensin converting enzyme 2 -ACE2); on the surface of human respiratory tract and lung cells); Invasion: then the virus either enters the host cell in some way (such as membrane fusion) or directly injects genetic material into the host cell; Shelling: Immediately after the viral infectious nucleic acid is released from the capsid; Biosynthesis: "non-stop" biosynthesis-synthesizing virus nucleic acid and protein according to gene instructions and with the help of raw materials, energy and places provided by host cells; Assembly: The newly synthesized virus nucleic acid and protein will be assembled into progeny virus; Release: the progeny virus is released outside the host cell.

Schematic diagram of virus replication

Schematic diagram of virus replication

Human body’s defense and counterattack

Both bacteria and viruses have to break through the human body’s defenses to complete the invasion, but the human body will eventually find their existence, and the human immune system has its own protective measures and early warning mechanism.

The first line of defense: skin and mucous membrane. The first way for human beings to protect themselves is defense, which makes the human body form a relatively closed system through the skin and mucosa. When harmful substances are about to invade the human body, the skin and mucosa will block the external pathogenic factors out of the body.

The second line of defense: bactericidal substances and phagocytes. There are always bactericidal substances and phagocytes patrolling the mucosal surface and inside the human body to prevent the invasion of pathogens. Take lysozyme as an example, it can destroy the cell wall of bacteria, cause the contents of the cell wall to escape and dissolve the bacteria, and can also directly combine with negatively charged virus proteins to form double salts with DNA, RNA and apoprotein, thus inactivating the virus. Therefore, the enzyme has antibacterial, anti-inflammatory and antiviral effects.

The third line of defense: specific immunity. When the powerful pathogen broke through the first two lines of defense, the human body’s counterattack just began. Through the phagocytosis of phagocytes and the analysis of special immune cells (T cells), the human body has produced antibodies that can specifically recognize invaders. The antibodies can make pathogens stick together and no longer be invasive, and finally the pathogens exposed between cells will be killed. But is the virus that invaded the cell safe? No! The human body can subtly identify which cells are infected by the virus, and then send a "killer" to kill the infected cells and release the virus inside the cells for antigen elimination.

However, it takes time for the human body to fight back, and pathogens will invade and occupy the human body through such a time gap!

Auxiliary appearance: drug therapy

Bacterial infection once became the greatest enemy of mankind. For example, the plague was called the "Black Death" in Europe, which reduced the population of Europe by one third in three years. At present, plague and cholera are classified as Class A infectious diseases in China. It was not until the discovery and popularization of antibiotics that human beings controlled the outbreak of bacterial infection.

Antibiotics mainly kill bacteria by destroying the structure of bacterial cells, such as cell wall, cell membrane, changing internal metabolism, hindering the synthesis of nucleic acid and protein, etc.

Chemical structural formula of penicillin

Chemical structural formula of penicillin

However, antibiotics are ineffective against viruses! Because bacteria and viruses have completely different structures!

Because bacteria have cell walls, as well as their own nucleic acid replication machines and ribosomes, antibiotics can kill bacteria with little side effects on humans as long as they are designed for these targets. However, the virus has no cell wall, its own nuclease and ribosome, and all its functions depend on the host cell. So antibiotics can’t kill viruses (we can’t make an "antibiotic" that kills host cells).

The ideal antiviral drugs can not only act on one or several links of the virus proliferation cycle, but also interfere or block it without affecting the normal metabolism of host cells. For example, ribavirin, a common drug, provides a large number of nucleotide analogues, which replace normal nucleotides, making the virus lose its replication ability and play a role in inhibiting virus amplification (but it also has great side effects on human body). In addition, the anti-influenza drug oseltamivir works by blocking the release of the offspring virus.

In view of this pneumonia epidemic, researchers from Wuhan Institute of Virology, China Academy of Sciences and Academy of Military Medical Sciences have also preliminarily screened out ramidivvir (GS-5734, phase II clinical anti-Ebola drug) and Chloroquine (Sigma-C6628, antimalarial drug) which have good inhibitory effects on novel coronavirus (2019-nCoV) at the cellular level.

But we have to say that in the face of virus treatment, human beings have never found a universal specific drug like antibiotics. Active treatment is to mobilize the human body’s own immune ability to fight against viruses, because only organisms themselves really know how to fight against organisms.

A number of economic data continue to improve China’s high-quality development and "full of vitality"

CCTV News:The latest statistics show that since the beginning of this year, China’s industry, light industry, retail and other fields have continued to pick up.

Since the beginning of this year, the revenue of industrial enterprises in China has improved significantly.

According to the data released by the National Bureau of Statistics recently, in the first two months, the operating income of industrial enterprises above designated size increased by 4.5% year-on-year, which was 3.4 percentage points higher than the annual revenue growth rate of last year. The recovery trend of enterprises was obvious, creating favorable conditions for profit growth. Among the industrial enterprises above designated size, the profits of state-owned holding enterprises increased by 0.5% year-on-year, the profits of private enterprises increased by 12.7%, and the profits of foreign-invested enterprises from Hong Kong, Macao and Taiwan increased by 31.2%. The profits of large, medium and small enterprises increased by 8.0%, 6.0% and 18.9% respectively.

In the first two months of this year, the light industry economy rebounded.

According to the data released by China National Light Industry Federation, 1-mdash; In February, there were more than 130,000 light industrial enterprises above designated size, achieving an operating income of 3.26 trillion yuan, a year-on-year increase of 4.1%. The production of light industry shows a rapid growth trend. The market vitality of light industrial consumer goods has gradually increased. In the first two months, the retail sales of 11 categories of light industrial goods reached nearly 1.3 trillion yuan, up 5.2% year-on-year. The export volume of light industry increased by 17.4%.

In April, China’s retail boom index was 50.4%.

According to the latest China Retail Prosperity Index released by China Business Federation, in April, China’s retail prosperity index was 50.4%, up 0.3 percentage points from the previous month, and remained in the expansion range for one year in a row.

At the end of March, China’s foreign exchange reserves rose to $3,245.7 billion.

According to the data released by the State Administration of Foreign Exchange on April 7th, by the end of March 2024, the scale of China’s foreign exchange reserves was US$ 3,245.7 billion, up by US$ 19.8 billion or 0.62% from the end of February. China’s economic recovery has been consolidated and strengthened, and the long-term positive fundamentals will not change, providing support for maintaining the basic stability of foreign exchange reserves.

The central bank set up 500 billion yuan for scientific and technological innovation and technological transformation refinancing.

On April 7th, the People’s Bank of China announced that in order to better meet the financing needs in the fields of scientific and technological innovation, technological transformation and equipment renewal, a second loan for scientific and technological innovation and technological transformation was set up, with a quota of 500 billion yuan and an interest rate of 1.75%. The distribution targets include 21 financial institutions such as policy banks, state-owned commercial banks and joint-stock commercial banks.

The special promotion meeting of "Investing in China" was held in Germany

Recently, the special promotion activity of "Investing in China" sponsored by the Ministry of Commerce of China was held in Stuttgart, Germany. More than 200 representatives of Chinese and German government agencies, enterprises and business associations attended the meeting to discuss the topic of investment in China.

China’s Ministry of Commerce said at the meeting that German investment in China accounts for 30% of EU investment in China. Bilateral economic and trade cooperation is not only the "ballast stone" of Sino-German relations, but also the "stabilizer" of China-EU relations. China’s emerging fields such as scientific and technological innovation, green and low carbon, and digital economy are full of business opportunities. Investing in China is a bright future for Sino-German economic and trade cooperation. Friedrich, chairman of the German-Chinese parliamentary group of the German Bundestag, said that German-Chinese economic and trade cooperation is a model of globalization, and the two countries should work together to meet the challenges and bring greater certainty to German-Chinese enterprise cooperation.

Data show that Germany has been China’s largest trading partner in Europe for 49 consecutive years, and China has been Germany’s largest trading partner in the world for 8 consecutive years. Sino-German trade accounts for about 30% of China-EU trade.

China’s first deep geothermal scientific exploration well exceeding 5000m.

The reporter learned from China Petrochemical that China’s first over 5,000-meter deep geothermal scientific exploration well — — Well Fushen Re 1 is expected to be drilled to 5,200m underground today (April 8th), setting a new record for geothermal exploration in China. Well Fushen Re-1 is located in Haikou City, Hainan Province. It is located in the high-temperature geothermal belt around the Pacific Ocean, one of the four high-temperature geothermal zones in the world, and it is a rich area of deep geothermal resources.
Previously, the geothermal resource reservoir with the temperature of 150 degrees Celsius was drilled in Fushen Re-1 well near 3,900 meters underground, and the geothermal reservoir with the temperature of 188.71 degrees Celsius was drilled in the depth of 5,123 meters.

5.189 million people entered and exited the country during the Qingming holiday.

On April 7, the National Immigration Bureau released data showing that during the Qingming holiday this year, a total of 5.189 million Chinese and foreign personnel entered and exited the country, an increase of 69.6% over the same period last year. Among them, mainland residents entered and exited 2.422 million people, an increase of 101.7% over the same period of last year; Foreigners entered and exited 500,000 people, an increase of 163.2% over the same period of last year; Hong Kong, Macao and Taiwan residents entered and exited 2.267 million people, an increase of 35.9% over the same period last year.

The inspection and release hall for vehicle-mounted personnel at Hengqin Port was officially opened on the 9th.

The inspection and release hall of passenger and truck combined with one-stop lane attendant at Hengqin Port has been completed and will be officially opened on April 9. There are 22 passages in the inspection and release hall for vehicle-mounted personnel, with 11 passages in the entry and exit directions, including 8 passages for quick inspection and 3 passages for manual inspection, all of which adopt the inspection mode of "cooperative inspection and one release".

Super-long cruise ships docked in Tianjin, and nearly 2,000 international tourists started the Beijing-Tianjin tour.

On April 7th, the cruise ship "Ocean Melody" carrying nearly 2,000 tourists from all over the world docked at the home port of Tianjin International Cruise, and tourists from the United States, Canada, France and other countries officially started a two-day tour of Beijing and Tianjin. The 275-day round-the-world travel route operated by this cruise ship is the longest round-the-world route at present.

Heilongjiang: More than 500 white-headed cranes fly to Wuyuer River Nature Reserve.

Over the past few days, more than 500 national first-class protected animals, white-headed cranes, have been welcomed to Wuyuer River Nature Reserve in Heilongjiang. These cranes bow their heads in the wetlands or wander in the water, adding agility and vitality to the earth in spring. Every year, during the spring migration season, the crane stops here for more than 30 days to replenish, and then continues to fly north to the breeding ground.

Shantou eπ 008 price reduction is coming, the reserve price 188,600! only this time

[Autohome Shantou Discount Promotion Channel] Recently, there are promotions underway. The highest discount has reached 28,000, and the minimum starting price is 188,600. If you are interested in this model, you may wish to pay attention to the details of the discount and click "Check the car price" in the quotation form to get higher discounts.

汕头eπ008降价来袭,底价18.86万!仅此一次

eπ008拥有时尚动感的前脸设计,进气格栅采用流线型的设计,增强了空气动力学效果。车身线条流畅,整体风格简约而不失个性,展现出强大的科技感与未来感。

eπ008车身尺寸为5002*1972*1732mm,轴距达到3025mm,车身线条流畅,展现出动感的轮廓。前后轮距均为1650mm,确保车辆的稳定性和操控性。此外,eπ008配备了265/45 R21的轮胎,搭配时尚的轮圈设计,进一步提升了整车的运动感和视觉效果。

汕头eπ008降价来袭,底价18.86万!仅此一次

eπ008的内饰设计现代且富有科技感,中控台上配备了一块15.6英寸的大尺寸中控屏幕,支持多媒体系统、导航、电话、空调的语音识别控制,为用户提供便捷的操作体验。方向盘采用皮质包裹,手感舒适,并具备手动上下和前后调节功能,让驾驶员能够根据自身需求调整合适的驾驶位置。前排座椅采用仿皮材质,具备加热、通风功能,并且驾驶位座椅还配备了头枕扬声器,增加舒适度和娱乐体验。座椅支持电动记忆功能,前排座椅和副驾驶位可以存储和调用预设的坐姿设置。后排座椅同样支持电动调节,包括前后移动和靠背角度调节,还配备了腿托调节,确保乘客的舒适度。第二排座椅可进行比例放倒,方便装载行李物品。此外,车内还设有多个USB和Type-C接口,为乘客提供便捷的充电需求,并且前排座椅还配备了无线充电功能,方便用户为手机充电。

汕头eπ008降价来袭,底价18.86万!仅此一次

eπ008搭载了一台高性能发动机,其最大功率可达200千瓦,最大扭矩为340牛·米,为车辆提供了强劲的动力输出和平顺的驾驶体验。

汽车之家车主 表示,外观真的很大气,尤其是黑色,和朋友的理想L7相比一点都不逊色。

Rene Liu sang Andy Lau’s new movie Wang Baoqiang forwarded that she remembered 16 years ago.

The ending song "Crowd" of the movie "Crowd" MV

The ending song "Crowd" of the movie "Crowd" MV

Wang Baoqiang and Rene Liu.

Wang Baoqiang and Rene Liu.

On December 31st, Rene Liu shared the MV of the ending song "Crowd" that he sang for the movie "Crowd" in Weibo, saying: "I can sing the ending song of" Crowd "more because I know Hua Ge, and Andy Lau starred in this movie. In the crowd, we once met and missed each other. After each meeting, we will go in different directions, may meet again, may walk on different roads, and miss each other far away. Who will you meet on the last day of 2020? What do you miss? How would you sing this song in Crowd? "

Later, Wang Baoqiang forwarded this Weibo and said, "After listening to this song, I remembered the days 16 years ago, and I will always remember the companionship and encouragement my sister and Brother Hua gave me. Thank you for meeting you’. " It is reported that Wang Baoqiang met Rene Liu and Andy Lau in 2004 for filming world without thieves, in which Andy Lau played Wang Bo, Rene Liu played Wang Li and Wang Baoqiang played Silly Root. Fan comments: "Thanks for meeting, Brother Bao keeps going", "Stupid root at that time, come on".

Pre-sale of 199,000 Star Road Star Era ET opens pre-sale.

  [car home Information] On April 15th, Starway (|) officially opened for pre-sale.The new car has launched a total of 8 configuration models.,The pre-sale range is 199,000-329,000 yuan.. The new car is based on Chery’s brand-new E0X global ultra-comfortable high-performance electric platform, positioning medium and large SUVs and providing two power options: pure electric and extended range. The new car extended range version has a pure battery life of 200km and a comprehensive battery life of 1500km+. The pure electric version will provide 77kWh and 100kWh battery versions, covering different cruising ranges of 540-760km.According to official information, the pure electric series of ET will be delivered as soon as it is pre-sold, and the extended range series of ET will be delivered in May.

Xing tu xing Ji yuan ET Presale price car make and model Pre-sale price (ten thousand yuan) Extended range Plus 19.9 Extended range Pro 21.9 Extended range Pro+ 23.9 Pure electric 625km Pro 23.9 Pure electric 540km Pro four-wheel drive 24.9 Pure electric 625km Pro city intelligent driving 25.9 Pure electricity 760km Max 28.9 Pure electric 655km Ultra 32.9

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● New car features:

Xing tu xing Ji yuan ET 2024 double motors

Xing tu xing Ji yuan ET 2024 double motors

  From the appearance, the ET in Xingji Era has a steady atmosphere, the front design is simple and avant-garde, and the LED penetrating light belt is matched with the lower light language to create a technological dreamy visual effect. The disappearing middle net is a typical feature of new energy vehicles. This design also highlights the EXEED Star Road brand logo, and the front enclosure is decorated with different materials and colors to create a layered feeling.

Xing tu xing Ji yuan ET 2024 double motors

Xing tu xing Ji yuan ET 2024 double motors

  The younger and even a little sporty roof curve and waistline are used on the side of the body of Xingjiyuan ET. Frameless doors and hidden door handles are all common configurations of new energy vehicles nowadays, which cooperate with large rims to create an atmospheric field. In addition, the car is also equipped with a roof lidar, which is expected to support a high level of driver assistance. In terms of body size, the length, width and height of the new car are 4955/1975/1698mm and the wheelbase is 3000mm respectively.

Xing tu xing Ji yuan ET 2024 double motors

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[New car and front case]

  The shape of the rear end is very full and round, and it also uses a penetrating taillight group. This penetrating taillight contains 262 LED beads, and the lighting effect is quite exquisite. The front of the new car is treated with bright black from the side skirt to the rear bumper, so that the body will not be too dull and create a strong sense of integrity.

Xing tu xing Ji yuan ET 2024 double motors

  The interior of Star Era ET incorporates the design concept of "Welcome Home", and the light color style creates a warm and simple style. According to the official introduction, high-end environmental protection materials such as marble slate, real wood decoration and Microfiber microfiber are also used in the car. The style of steering wheel is rare, with flat bottom and two spokes, which is a bit like the style of concept car.

Xing tu xing Ji yuan ET 2024 double motors

Xing tu xing Ji yuan ET 2024 double motors

  The 15.6-inch 2.5K central control large screen in the center console is very eye-catching. The smart home voice based on the Lion AI big model includes 20 smart home scenes such as car home interconnection, baby mode, pet mode and karaoke mode, which endows more home attributes for Star Age ET. At the same time, the center console also broke the traditional fixed instrument panel mode, equipped with an electric sliding auxiliary instrument panel and a "star-moving bar", with double-layer storage compartments and warm atmosphere lights, so that passengers in the car can experience the comfort without barriers. In addition, the front and rear rows can be electrically moved by voice or physical buttons, which further improves the flexibility of the interior space.

Xing tu xing Ji yuan ET 2024 double motors

Xing tu xing Ji yuan ET 2024 double motors

  Xingjiyuan ET also has a "home theater" with 7.1.4 panoramic sound and 23 speakers, and a 2.38㎡ canopy to improve ride comfort. Among them, the double-layer flow and three-temperature heat pump air conditioner can quickly reach a comfortable temperature of 18℃ in the low-temperature heating test. At the same time, Star Age ET is equipped with intelligent driving system and high-performance sensing hardware.

Xing tu xing Ji yuan ET 2024 double motors

  In terms of power, Xingjiyuan ET pure electric version provides two sets of power systems: single motor and double motor. The maximum power of the single motor version is 230kW, and the peak torque is 425N·m, 6.4 seconds and 6.6 seconds. Two-motor four-wheel drive model, the front axle motor entry version is 123kW, the high version is 183kW, and the maximum power of the rear axle motor is 230kW. The peak torque is 238N·m before and 425N·m after the PRO four-wheel drive version. The Ultra version is 266N·m before and 425N·m after, and the fastest Ultra can "break 100" in 3.8 seconds.

  In terms of configuration, except for two models with minimum extended range, other models are equipped with air suspension +CDC continuous damping and vibration reduction control system as standard.In terms of intelligence, Star Age will launch a map-free scheme for urban assisted driving in the fourth quarter of this year.

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  Star Era ET will be equipped with Contemporary Amperex Technology Co., Limited Shenxing rechargeable battery, which is available in 77kWh and 100kWh. Relying on the global 800V platform, it can drive 400 kilometers in 10 minutes at 25℃ room temperature. It only takes 24 minutes for the SOC to be 20%-80% in the extremely cold environment at MINUS 20℃, which effectively solves the problem of tram charging for northern users.

  The extended-range version of Star Era ET will be equipped with a 1.5T turbocharged engine with the engine model SQRH4J15B, and equipped with a plug-in hybrid system. The engine can output a maximum power of 115kW, a peak torque of 220N·m, a maximum motor power of 195kW, a maximum torque of 324N·m, and a "breaking 100" in 7.8 seconds. The extended range version is equipped with a 32kWh battery pack, with a pure battery life of 200km and a comprehensive battery life of 1500+km.

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Competitive product analysis:

Xpeng Motors Tucki G9 2024 570 Pro

"Tucki G9"

Aouita Science and Technology Aouita 11 2024 HarmonyOS Edition Zhixiang Upgrade 90-degree Luxury Edition

Aouita 11

AITO asks the community M7 2024 1.5T intelligent driving four-wheel drive Max version 6 seats.

Wen Jie M7

LI Ideal L7 2024 Pro

Ideality L7

Tengshi Automobile Tengshi N7 2024 630 Four-wheel Drive Smart Max Edition

Tengshi N7

  Star Era ET locates medium and large SUV models, providing pure electric and extended range power systems. In view of the pure electric market, its main competitors are nothing more than Tucki G9, Aouita 11, Haobo HT and so on. In the extended range market, competitors have become rich, such as some popular products in the near future, such as Jiejie M7, Ideal L7, Lantu FREE, Tengshi N7, etc. The above-mentioned products have good competitiveness in the market, and each of them has strong product labels. With the rich choice of two kinds of power and the blessing of intelligent auxiliary systems, Xingjiyuan ET is expected to compete in the competition.

Full text summary:

  At present, competitors in the large and medium-sized SUV market, such as Yunyun, are also rolling even harder, which makes Xingjiyuan ET face considerable competitive pressure when it enters it. We should know that the Star Age is an extension to the direction of electrification on the basis of the high-end star route, and its goal is to create the ultimate comfortable travel experience for users. Xingjiyuan ET focuses on the mobile meeting room, and it will also have a good performance in intelligent driving, which lays a good foundation for entering the medium and large SUV market. Now that the pre-sale price of the car has been announced, I look forward to the performance after the subsequent listing. (Text/car home Li Na)

Ministry of Foreign Affairs: I hope the giant panda can better play the role of "envoy" of Sino-Japanese friendship.

Xinhua News Agency, Beijing, June 17 (Reporter Hou Xiaochen) Foreign Ministry spokeswoman Lu Kang confirmed on June 17 that Xiang Xiang, a giant panda cub born in Japan, will be returned to China on a delayed date by mutual agreement between China and Japan.

Lu Kang said at a regular press conference on the same day that according to the Agreement on Cooperation between china wildlife conservation association and Tokyo, Japan for Joint Research on Giant Panda Protection, Xiangxiang, a giant panda cub born in Ueno Zoo in Tokyo, should have been returned to China when it was two years old. Now, with the agreement reached and signed by China and Japan, Xiangxiang’s return to China will be delayed for one and a half years until the end of December 2020. At present, the relevant agreement has come into effect.

Lu Kang said that the giant panda is a national treasure of China and a "messenger" to promote friendly exchanges between China and foreign countries. China is very happy to see that Xiangxiang has been taken good care of and received friendly hospitality during her stay in Japan. China can feel the Japanese people’s love and reluctance to give up from every detail. Now, at the request of Japan, China agrees that Xiangxiang will stay in Japan for a longer period of time. "We also hope that this decision will enable Xiangxiang to play a better role as an ambassador of Sino-Japanese friendship."

Mercedes-Benz EQE in Qujing area is offering a discount, with a minimum price of 428,000! limited in number

[car home Qujing Preferential Promotion Channel] At present, there are large-scale preferential activities in Qujing area, with the highest discount reaching 50,000 yuan, making the minimum starting price only 428,000 yuan. If you are interested in Mercedes-Benz EQE, you may wish to click "Check the car price" in the quotation form and strive for higher discount.

曲靖地区奔驰EQE正在优惠,最低售价42.8万!数量有限

Mercedes-Benz EQE adopts a family-oriented front face design, and the front grille adopts a closed design with streamlined body lines, which highlights the unique style of electric vehicles. The LED headlight group at the front of the car is closely connected with the front grille, creating a strong visual impact. On the whole, the overall shape of Mercedes-Benz EQE is simple, stylish and luxurious.

曲靖地区奔驰EQE正在优惠,最低售价42.8万!数量有限

Mercedes-Benz EQE has a body size of 4969*1906*1514 mm, a wheelbase of 3120 mm, a front tread of 1634 mm and a rear tread of 1645 mm.. Its smooth side lines match the right proportion of the car body, showing the elegant demeanor that a luxury car should have. In addition, the car is equipped with 255/45 R19 tyre size, which complements the exquisite 19-inch rim, further enhancing the sense of movement and texture of the whole car.

曲靖地区奔驰EQE正在优惠,最低售价42.8万!数量有限

The interior design of Mercedes-Benz EQE shows a sense of luxury and technology, and the steering wheel made of leather has electric adjustment function, which makes the driver more convenient to operate. The 12.8-inch large screen on the center console adds a technological atmosphere to the vehicle, and supports various voice recognition controls such as multimedia system, navigation, telephone, air conditioner and sunroof. In terms of seats, Mercedes-Benz EQE is made of imitation leather. The main and co-pilot seats are equipped with heating and ventilation functions, and it supports electric adjustment, including front and rear, backrest, height (4-way), leg rest and lumbar support adjustment, and also has memory function. In addition, the front row and the rear row are equipped with a Type-C interface and a USB/Type-C interface respectively, and the front row also has the function of wireless charging of mobile phones. These configurations not only enhance the driving experience, but also reflect the luxury and comfort of Mercedes-Benz EQE interior.

Mercedes-Benz EQE is equipped with a powerful motor, which can output the maximum power of 350 kW and the maximum torque of 858 Nm, bringing excellent power performance and driving pleasure to drivers.

The owner of car home said that although the price of Mercedes-Benz EQE was slightly higher than the budget, it was excellent in appearance, internal comfort, configuration and battery life, and its cost performance was quite good.

Man was sentenced for smashing subway station glass with a slingshot to vent his emotions.

  Beijing Youth Daily News In order to vent his emotions, he used a slingshot to shoot a projectile. The man Anmou broke three glass curtain walls in the East Hall of Houshayu Station of Beijing Metro Line 15. Yesterday, the Beijing Youth Daily reporter was informed that the Shunyi court sentenced Anmou to two years in prison and suspended for two years for the crime of seeking trouble.

  At 19 o’clock on April 11, 2019 and at 21 o’clock on May 10, 2019, Anmou drove a truck from north to south on Jingmi Road, passing through the east side of Houshayu Station of the subway, and used a slingshot to fire bullets to vent his emotions. Three glass curtain walls in the east hall of Houshayu Station of Line 15 subway were broken.

  It is reported that "bullet holes" appear in the glass curtain wall of Houshayu Station in Shunyi, Metro Line 15. Police officer Zhao of the Criminal Investigation Detachment of the Public Transport Corps of Beijing Public Security Bureau said: "This kind of special glass is not easy to break if it is not acted by external force, and scattered steel balls are found on the spot." After receiving the report, the Criminal Investigation Detachment of the Public Transport Corps set up a task force in conjunction with the police station of Fengbo Station and sent a number of investigators to investigate.

  At about 9: 50 pm on May 11th, an investigator found that when a closed pickup truck passed Jingmi Road outside Houshayu subway station, the driver rolled down the window and took out a slingshot, "shooting" at the glass curtain wall and quickly fled after breaking the glass. Then the police quickly found the man Anmou in a community in Houshayu and arrested him.

  "We got more than 90 steel balls, 11 clay balls and a slingshot in the car." Zhao police officer said that when he saw the arrival of the police, Anmou confessed his behavior. "Breaking the glass to vent his dissatisfaction, I regret it now."

  Anmou, a water delivery worker, said that he was in a bad mood because of conflicts with his family. In order to vent his emotions, he took out his slingshot and shot steel balls on the glass when he walked to Jingmi Road outside Houshayu subway station. After driving around, I shot at the second glass.

  After identification, the loss price of three damaged glass curtain walls was 62,700 yuan. His family has compensated the victims for their losses. Anmou obtained the understanding of the victim unit. Anmou was prosecuted to Shunyi court for allegedly seeking trouble.

  After trial, the court held that Anmou arbitrarily damaged public property, and the circumstances were serious. His behavior violated the social public management order and constituted a crime of seeking trouble and should be punished. In view of the fact that Anmou truthfully stated the facts of the crime, pleaded guilty and repented, and had compensated the injured unit for economic losses and obtained understanding, he was given a lighter punishment and suspended sentence according to law. In the first instance, the court sentenced Anmou to two years in prison and suspended for two years for the crime of seeking trouble.

  (Beijing Youth Daily reporter Song Xia correspondent Geng Ruoshi)

Interview | The director gave all responses to the controversy of "Door Lock"!

Producer 500, director Buick accepted an exclusive interview with 1905 Film Network.

Special feature of 1905 film network In director Buick’s mind, the film can be better, because many of the original contents of the script were taken away by him because of the length of time.

 

Then, in his view, how many points can this version of "Door Lock" with still guaranteed standards have? With this curiosity, we walked into his various responses to Door Lock.

 

Stills of "Door Lock"


Since the release of the film "Door Lock", the evaluation has its own controversy. As a movie, this is the norm. Whether it’s producer 500 or director Buick, it’s already predicted.

 

In the eyes of 500, this controversy happens to be the charm of Buick as a new director. He has all the courage of young people, and he also has insufficient experience in directing a tube.

 

No matter what the audience’s recognition of the essence of the film is, we can pay attention to the security situation of women living alone from "Door Lock", and perhaps this film has been successful. As Bai Baihe said at the premiere, attention itself is a kind of strength.



01 create

After Buick won the Best College Student Short Film Award in the 8th China International New Media Short Film Festival with the short film "Salvation", he received many scripts.


Director Buick accepted an exclusive interview with 1905 Film Network.

Without exception, these scripts are mostly remakes of suspense themes. In addition to "Door Lock", what impressed him deeply was a work related to the escape of the Chamber of Secrets.

The theme of suspense and horror is Buick’s preferred style. Even in the short film "Salvation" with the theme of war, we can also gain insight into his ability to control this type. 

 


If we simply want to make the suspense type to the extreme in form, then the story of the escape from the Chamber of Secrets can already be supported, but from the content level, there is still something missing as a whole. At the suggestion of 500, and combined with his own experience, Buick finally chose "Door Lock".


Five hundred was the judge of the short film award at that time. In his eyes, this new director is very special, and he has wildness that other domestic directors don’t have. If possible, two people can make a big ticket together.

 

Producer 500 accepts an exclusive interview with 1905 film network

However, Buick only has short film experience, from short to long, which is not simple. He knows that he needs a springboard, and 500 knows that this "dumb-headed" needs more practical experience in order to better shoot feature films.

 

Five hundred handed Buick the book of the series aiming. After watching it, Buick was poked by the very cinematic narrative of the previous episodes, and then took it down. However, commercial works are no better than students’ short films, and each type of work corresponds to different staff. Directors also need to have stronger leadership and external communication skills.

 

During the filming of Aiming, 500 made Buick more immersed in creative work. But when it came to "Door Lock", he really "pushed" Buick out.

 

As a producer, 500 gave Buick a lot of advice in the early stage of script creation. The script was read over and over again, and then the shortcomings were found in the middle to fill this gap. As a new director, Buick hopes to highlight his own style to the extreme in this work.


Five hundred rejected the idea. "There is still some life-oriented content in this movie to touch the more emotional places of the audience."

 


During the whole preparatory stage, Buick will have his own anxiety, and he will fall into a strange circle — — Why are these things different from what you think?


Five hundred told him, "The farthest distance between people is’ I thought’". In the communication between the crew, we must not simply use abstract words such as texture to describe it, but must form more specific words or pictures so that the crew can understand it.

 


Combining these valuable experiences, the script was also changed to a more satisfactory version, and Door Lock was formally established and started in Xiamen in September 2020.

 

02 "hiding the murderer"

When Buick got the script, it had made some adjustments compared with the original story, but in their view, these adjustments were far from enough, especially where suspense was hidden.

 

Do you want to hide? How to hide it?


The most curious thing about "Door Lock" is the identity of the man in black. For suspense movies, decryption is something that the audience can’t wait to do in the process of watching movies. If the identity of the man in black is put at the end, but the audience guesses it in advance, the whole mystery laid in the early stage will become very embarrassing.

 

"You should never think that you are smarter than the audience. Now the audience is too smart. The more you hide, the more self-defeating. In this case, it is better not to hide. " Five hundred, who is quite experienced in suspense subjects, gives his own bottom in his creation.

 

Buick also found a creative idea. "I don’t want to make a pure suspense film. The murderer is not the key issue, but the female issue is."

 

After the problem of "hiding the murderer" was solved, Buick’s creation also took shape. For example, in the subway, Fang Hui (played by Bai Baihe) and Qiao Xiaoman (played by Qiao Xiaoman) have a more definite place.



Even so, in the process of creation, 500 and Buick still had some disputes.


Five hundred told Buick that Fang Hui and the boss must be filmed in the movie. But in Buick’s view, it is not necessary. If there is already a scene in the movie where Fang Hui is harassed in the office in order to show the weakness of women in the workplace, then the drama of the wine bureau is very cumbersome.

 


"Door Lock is about women’s independence. She is not only in the office, but also in all aspects of life. Then the wine bureau is an essential drama, and this is also a place where the audience can be more empathetic." Of course, 500 did not strongly ask Buick to add this content. "You can shoot it first, and then deal with it when editing."

 

Finally, in the editing stage, there were two versions as a whole; One is more life-oriented, and the other is more typed. From the perspective of genre preference and lens design during shooting, Buick is not satisfied with the life-oriented version, but he understands that "Door Lock" is to let the audience pay attention to women’s safety issues, so pure genre expression will weaken its power.

 


Combined with the story of life flow and stylized type expression, in Buick’s view, the most complete version of "Door Lock" should be two and a half hours. "The story should be one thing that Fang Hui experiences every day, which slowly accumulates and finally erupts." However, this version does not meet the requirements of a genre film, which is not conducive to the audience’s impression and the cinema’s film arrangement.

 


Recalling the entanglement in the editing, Buick did not forget to reflect. "These problems can actually be avoided from the script stage. If the plot is set in place reasonably, there will not be so many plot pictures that cannot be abandoned during the editing process."

 

03 cut down

"If you follow my script, it is actually particularly suitable for processing into a mini-drama with three or four episodes, and each character will have a good display." However, as a film, "Door Lock" must be cut by Buick.

 

In the original version of Door Lock, the opening was as long as 15 minutes. In the view of 500, this paragraph can be presented to the audience as a short film in the form of a pilot notice.



"There is actually her ex-boyfriend in front of the story, from the girl going home to meeting her ex-boyfriend, including the atmosphere in the corridor. Moreover, in that kind of old building, when you open the door, you may hear a cough upstairs. These thoughtful and fearful things have all been written in by me. And in that story, there are still some conversations between her and her ex-boyfriend, which explain the background of many characters. "

 


Buick read a lot of news information and combined with his own experience to create this story. Including the opening, many viewers will be curious, why do men in black lie on the top of the wardrobe? "These are not my whimsical creations, but there are cases that can be studied in reality."

 

In addition, in the story line of the dog farm at the end of the film, there is also a very important scene, which was deleted for the sake of time. This also indirectly led to the current audience’s controversy over the plot in the second half of the film.

 


"It was a self-help drama of Fang Hui, and the whole narrative was edited in parallel from the perspectives of Fang Hui and Zheng Fei (played). Fang Hui was in a coma and remembered Qiao Xiaoman’s saying in the subway,’ Hold on, hold on, that’s how you were domesticated’. Then she slowly woke up and saw the door next to her closed and two dogs. She used the coma medicine left by Zheng Fei, and injected it into the sausage. As a result, a dog died directly after eating it. Then she directly pulled the main switch and the electronic door next to it opened. She found Qiao Xiaoman and pulled her up. Another dog ran after them. Although she passed the first door, she finally got stuck at the second door. At this time, Zheng Fei came back. Zheng Fei saw everything in front of him, and there was a line,’ Why did you kill my dog?’ "

 


In the original play, there are women’s self-help and the mutual help of "girl helps girl", and at the same time, it can let the audience see the emotional changes of the role of Zheng Fei in the later stage of madness.

 

Buick excitedly revealed these cuts to us, but he couldn’t help sighing that they were all caused by inexperience. "The next play will pay attention to these contents from the script stage."

 

04 Fei Zheng

Without the support of these stories, the audience have a better question about the role of Zheng Fei, and why he became such a person.

 

In Buick’s creation, Zheng Fei has a prototype.

 

"Why is his name Jeffrey? In fact, this man is a notorious pervert murderer in the United States. He is very similar to the situation in Zheng Fei. Their external images look good, but in the end, they are found to be very dark inside, and even do a lot of unsightly things. I remember the documentary at that time asked Jeffrey, saying that you have good conditions and good looks, why can’t you fall in love with people normally? The reason for his answer is’ because I want to’. The simple answer is that we can’t think with the logic of normal people at all. They pursue absolute control and must do things according to their wishes, which is the same as Zheng Fei’s strong desire for control. "

 


It is based on this idea that Buick insisted on retaining the dialogue between Zheng Fei and Fang Hui in the car during the deletion process. "In addition to explaining the background of the characters, this scene actually implies Fang Hui, and she has no right to know it. If you want to break this paper, it will be finished."

 

Although the audience will have a lot of questions and make the film controversial after the deletion of "Door Lock", in Buick’s view, this may be the deficiency of being a new director, and it is also a place to make up for it in the future.

 

As for "Door Lock", how many points do you give?


Buick said 70 points.


Innovative research and development, the whole process of "green" express packaging "slimming" is going on

CCTV News:As the major e-commerce platforms start mid-year promotion activities, since June, nearly 400 million express parcels have flowed across the country every day. However, in the interview, the reporter found that the big box is covered with small boxes, and the box is filled with plastic foam, and the goods … … There are still many such phenomena of over-packaging of express delivery.

CCTV reporter Tang Ying:These parcels are all goods I bought from different e-commerce platforms. Let’s take a look at their packaging. Let’s take a look at what’s in this big package. When we open the package, we first see a foam film, which has two layers. There are bought tea leaves in it. We measured the length of the two films, the short one is 105 cm and the long one is 165 cm. In fact, let’s try it. This short film can wrap the tea leaves, and it can also play a role in ensuring the safety during transportation.

The reporter calculated that the size of these removed packages is almost five times that of the purchased goods. Because many of them can’t be reused, they can only be sent to the garbage collection station, which has become the "main force" of domestic garbage.

General Station reporter Chen Qingbin:In the recycling station in this community, we see that the largest amount of recycling in the site is this kind of carton. These cartons have been sorted and arranged, in addition to some foam boxes and plastic articles like this. All the recycled items in this site will be recycled by recyclers every day.

       The staff told reporters that there are currently about 200 sites like this in Tianjin, and the daily processing and recycling volume is about 5 tons, of which express packaging waste accounts for about 80%.

Innovative research and development of green packaging to break through the technical cost difficulties

At present, China’s express delivery industry has an average daily business volume of 350 million pieces and nearly 700 million daily service users, ranking first in the world for many years. It is not only urgent to properly solve the problem of over-packaging of express delivery, but also the inherent requirement of industry transformation and upgrading and sustainable development. The key to "slimming" express packaging is to start from the source and work hard on packaging design. So, what about the research and development of recyclable green packaging? What is the difficulty of R&D and promotion? With this question, the reporter came to China Post Green Packaging Innovation Laboratory.

CCTV reporter Tang Ying:This is the research and development site of China Post Green Packaging Innovation Laboratory. The packaging prototype behind me is making samples according to the design drawings of the researchers.

Gao Kang, packaging engineer of China Post Green Packaging Laboratory:After the box is glued, it will undergo some physical tests such as falling, vibration and impact, which can meet the safety verification of the contents in real scenes. If it doesn’t meet the standard, we will consider making some adjustments from the paper it uses to increase the grammage of the paper, then we will make a material selection of the paper, then redraw the drawing, repeat this action, and then test it until it meets our requirements.

In addition to cartons, various items often used in express delivery, such as bubble film and adhesive tape, will be tested for many rounds. R&D personnel said that it is the focus and difficulty of R&D to wrap the tape frequently.

Kang Li, Technical Director of China Post Green Packaging Laboratory:Compared with the traditional ordinary adhesive tape, it may not be as strong as the traditional adhesive tape, reaching a level of 50%, and its cost has increased by nearly two times.

In order to solve this problem, Kang Li and his colleagues conducted numerous tensile tests and observed the curves in real time. After nearly two years of continuous efforts, a new type of biodegradable environmental protection adhesive tape was finally launched this year. When garbage is recycled, the adhesive tape can not be separated from the carton, and under suitable conditions, the adhesive tape can be directly degraded into water and carbon dioxide.

In the green packaging innovation laboratory, the reporter found that many recycling boxes that have been developed for a long time are rarely seen and used in daily life.

Kang Li, Technical Director of China Post Green Packaging Laboratory:The scene it uses is relatively fixed at present. It (needs) to be able to sign in person and take back the box. If this (if) is put in the self-reporting cabinet, it is difficult for the courier to recycle it. As a courier company, its loss rate is also relatively high, so we need to build an intelligent management system step by step now.

       Kang Li told reporters that at present, the usage of recycling bags in China’s postal enterprises has reached 96%. However, compared with the business volume of postal enterprises and the whole industry, there is still much room for improvement in the usage and recycling times of recycling packaging at the end of express logistics.

Express delivery enterprises explore and promote the "greening" of the whole process

Express packaging should not only ensure the safety of goods, but also avoid waste. How to find a balance between the two? In the investigation, the reporter found that more and more express logistics enterprises attach importance to and think about this issue, and promote the "greening" of the whole process in various ways to "slim down and reduce the burden" for express packaging.

At a courier outlet in Yiwu, Zhejiang, the reporter saw that the green delivery block was specially divided. Consumers can accumulate the number of express packages they bring and exchange them for delivery fees between different cities. In the transportation link, express delivery companies have replaced the former 9.6-meter van with a high-capacity trailer with a length of 15 to 17 meters, which can reduce the pollutant emissions per unit express by more than 70%. Following the transport vehicle, the reporter saw the green smart environmental protection bag in the sorting center.

Zhu Zhongchen, Deputy Manager, Personnel Integrated Management Group, Yiwu Center, Zhejiang, ZTO Express:This package is now recycled more than 110 times, and a chip is inserted at the same time, so that it can be automatically sorted in this system. Through the popularization and application of E-mail, we can reduce the pollutant discharge of paper by more than 60% in the later transit link. Basically, we have achieved a recycling of everything now, which actually creates a closed loop, which truly reflects a core green environmental protection value.

       In the postal processing center in Guizhou, the reporter saw that many e-commerce products began to use a green circulating clearing box. Compared with traditional cartons, this box no longer needs tape sealing, and the box comes with a lock, just sticking a self-adhesive address sheet.

The proportion of no secondary packaging is expected to reach 90% by the end of this year.

As a big country of express delivery, the management of over-packaging of express delivery has always been a common concern of all walks of life. As early as 2009, China carried out special treatment of express packaging. In April 2021, the State Post Bureau issued the "Special Treatment Plan for Overpackaging and Random Packaging of Mail Express". After many efforts, the green development awareness of the express delivery industry has gradually increased. The relevant person in charge said that by the end of this year, we will strive to achieve 90% of e-commerce express mail no longer being repackaged.

According to the latest data of the State Post Bureau, according to the parcel spot check in May, 380 million pieces of mail express with recyclable packaging were used, and 350 million corrugated boxes with good quality were recycled. In March this year, the State Post Bureau issued the "Implementation Opinions on Promoting the Green and Low-carbon Development of Postal Express Industry", which clearly stated that it is necessary to speed up the construction of a recycling system for mail express packaging and promote the construction of a pilot project for the large-scale application of recyclable express packaging supported by the National Development and Reform Commission.

Guan Aiguang, Deputy Director of Market Supervision Department of State Post Bureau:The green management of express packaging involves many subjects, long chain and wide fields. In the process of promotion, all departments need to work together to accelerate the formation of a situation of joint management; It is necessary for the state to introduce more preferential tax and fee subsidy policies and increase the supply of green packaging for express delivery; It is necessary for local government departments at all levels to increase support and solve the difficult problems such as high cost of recyclable packaging, difficult recycling and less support.

Guan Aiguang said that the promotion of green packaging is a systematic project. At present, with the wide application of green packaging such as electronic waybill, slimming tape and lightweight box, China has basically entered the 2.0 era of packaging reduction. In this period, it is necessary to turn to material and technological innovation, such as the development of new materials, new packaging containers, intelligent packaging systems, etc., to achieve the goal of collaborative reduction from the upstream and downstream of the supply chain.

On the other hand, the recycling packaging market at the end of logistics should achieve a technical breakthrough. Popularizing and applying recycling packaging is an important part of green postal strategy and an important means to explore the green transformation of packaging.

Guan Aiguang, Deputy Director of Market Supervision Department of State Post Bureau:By the end of the year, the proportion of e-commerce express mail will not be repackaged to 90%, and the two special treatments of over-packaging and plastic pollution will be further promoted. One billion pieces of mail express mail will be packaged by recyclable express delivery, and 800 million corrugated boxes with good quality will be recycled.